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What resources are available to the server (physical/virtual, CPU, memory, disk space, disk type, # of Exchange servers, etc.)?<br />
<br />
Also, what does your user landscape look like (# of users, Outlook vs OWA users, # of messages sent/received a day, etc.)?
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What resources are available to the server (physical/virtual, CPU, memory, disk space, disk type, # of Exchange servers, etc.)?

Also, what does your user landscape look like (# of users, Outlook vs OWA users, # of messages sent/received a day, etc.)?

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mahiummadi,<br />
<br />
Any update on your issue? &nbsp;Is it resolved? &nbsp;Are you still experiencing the issue?
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mahiummadi,

Any update on your issue?  Is it resolved?  Are you still experiencing the issue?

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Hi Guys <br />
<br />
We have installed Exchange 2016 and the server performance is very slow. Once we reboot the server it is alright for few days and then starts slowing down and finally come to a point where login take a long time , unable to open anything . Also when you move the Exchange database for the server the performance seem to improve. <br />
<br />
Any ideas what could be the cause ?
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Hi Guys 

We have installed Exchange 2016 and the server performance is very slow. Once we reboot the server it is alright for few days and then starts slowing down and finally come to a point where login take a long time , unable to open anything . Also when you move the Exchange database for the server the performance seem to improve. 

Any ideas what could be the cause ?

Windows server 2012 very slow with Exchange 2016

Windows Server 2012 is the server version of Windows 8 and the successor to Windows Server 2008 R2. Windows Server 2012 is the first version of Windows Server to have no support for Itanium-based computers since Windows NT 4.0. Windows Server 2012, now in its second release (Windows Server 2012 Release 2) includes Foundation, Essentials, Standard and Datacenter, and does not support IA-32 or IA-64 processors.