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Remote Connectivity shows attempting to test potential Autodiscover URL failed

We have recently renew SSL for our Exchange 2010 HUB/CAS server.  

Remote Connectivity shows attempting to test potential Autodiscover URL https://autodiscover.mydomain.com:443/autodiscover/autodiscover.xml Testing of this potential Autodiscover URL failed.  

However, when I do a https://autodiscover.casusa.com:443/Autodiscover/Autodiscover.xml from my PC, I am able to see the xml content.

Any idea of how to fix?

Thanks.
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Hallidays

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