Optimal settings for our Vulnerabilities apps installed and should we include Windows Defender

We have installed in our computer, a Windows 10 Pro OS, Spybot-Search & Destroy, Malwarebytes, Comodo Internet Security (which has Anti-Virus) and SUPERAntiSpyware.  Afer installing them, all are in memory at every startup.  We noticed that now the computer startup is bit slower, so started removing from memory both Malwarebytes and SUPERAntiSpyware leaving only Spybot & Comodo in memory on online protection.

2 questions:
  • What is EE opinion when multi  Vulnerabilities installed and is there recommendations on which to leave in memory?
  • Also we have Windows Defender in our Windows 10, but it is off.  What is EE opinion in also including in our apps of Vulnerabilities apps installed?
rayluvsAsked:
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rindiCommented:
Only malwarebytes and one antivirus software will coexist nicely with each other. I would remove spybot and super antispyware. Komodo as far as I know is an AV tool, so that can stay, although I'd rather recommend Panda AV as AV tool.
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rayluvsAuthor Commented:
As of Windows Defender?  What should we do?
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rindiCommented:
Windows defender disables itself when you install another AV product. It still receives Windows updates (signatures) even when disabled, so that's fine.
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