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RemoteApps using Remote Desktop Services

We are looking to setup RemoteApps on Server 2012 R2 on a virtual Hyper-V machine in order to run SIMS and PSF internally only to begin with but with the view to publishing externally in future. We are not looking to use full desktops just apps. We would be looking to have SIMS running constantly on 6 users and no more than 20 concurrent users total at any time. PSF wouldn't be used very often and not more than 10 users at a time (so potentially 30 concurrent users in total). Having looked around we are thinking of going with 4 processors, 20GB RAM and a 60GB hard drive.
Do you think this sounds enough?
Are there any known issues with using Remote Desktop Services on a Hyper-V machine?
Has any one else done this using a step-by-step guide from anywhere that they can recommend?
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winterhillschool

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Thanks for the suggestions so far.

Sorry SIMS is our Management Information System and PSF is our finance software.

I will test it with 10 users and then scale it up. Looking at its use when installed on physical computers I would say it would be similar usage to office 16

I don't believe there will be any issues with files locking or permissions but I will check.

I was looking at setting roaming profiles on a different server and then set a scheduled task to delete them every some many days. Does this sound reasonable?
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Of course, I should have thought about that, I will use GPO instead of a scheduled task to manage the profiles.

In the event the remote desktop profile needs to be deleted how would I go about this? bearing in mind we would only be using RemoteApps not full remote desktop sessions.
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I was thinking of the second two scenarios you mentioned we don't have anything citrix, is the userprofilemanager available to use separately?

What is the procedure to delete the profiles from the RDServer (is this the same as deleting profiles in control panel\system\advanced settings\user profiles settings?) and the central store?
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thanks for the help