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Change SMTP port on Exchange Send Connector

I can't seem to do anything outbound on port 25 from a certain client site. The ISP says they are not blocking the port. I've tried 2 different routers and the same issue exists.

Exchange 2010 is currently configured to send via Smart Host or port 25.

If I can get the Smart Host provider to reconfigure to listen on 587, can I just modify the Exchange Send Connector default port?

Set-SendConnector “ConnectorName” -port 587

Any issues with doing so?
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Ganesh Anand
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Please ready the setup guide at exchangepop3.com
If your smarthost can accept connection on port 25, then i don't see any issue to configure send connector on port 25.

The smarthost will send the email out to internet
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thanks!