Why this mail sent with empty email address in Exchange?

This is using MS Exchange 2010 Server. Sometimes, I browse to the queue viewer, and always found few mails were attempt to be sent to some very strange recipeints. However, these type of mails always stuck, and kept but die off after 2 days. To my surprise, the sender address is "<>" (see the attached jpg). What was happening, and why so many such mails were sending out? What can I do to stop this?

Thanks in advance.
-EE---Mails-send-from-empty-email-ad.JPG
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MichaelBalackAsked:
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AntzsConnect With a Mentor Infrastructure ServicesCommented:
This email was probably being sent by a user's email account which has been set with an OoO(Out of Office) auto reply.  Because it is being replied automatically there will not be a sender.
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MichaelBalackAuthor Commented:
Hi AntZs,

Okay I see.

However, the recipient that this mail sent to, is always using non-legitimate email domain.
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suriyaehnopCommented:
Try export the email to eml format then open it using outlook. Look for internet header, i think the actual sender email address available at "return-path" and "x-originating-ip"

To export mail to eml:
https://blogs.technet.microsoft.com/tkern/2011/02/14/how-to-really-export-multiple-messages-from-your-exchange-2010-queues/
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Tej Pratap Shukla ~DexterConnect With a Mentor Server AdministratorCommented:
Hi,
Antzs is saying right, these type of messages are sent as notifications. Because empty <> sender mail address is generally sent for removing the chances of loop creation within a network. Bye the way, these type of messages are neither general nor rare.
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MichaelBalackAuthor Commented:
Thanks for both experts - Antzs and Tej, in providing the answer. Really appreciate.
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