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Is it OK to run a system state backup while a server is running during work hours? &nbsp;This is a windows 2008 r2. I am looking to start backing up the system state but I am not sure if there are any rules about when this should not be run.
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Is it OK to run a system state backup while a server is running during work hours?  This is a windows 2008 r2. I am looking to start backing up the system state but I am not sure if there are any rules about when this should not be run.

system state backup

Windows Server 2008 and Windows Server 2008 R2, based on the Microsoft Vista codebase, is the last 32-bit server operating system released by Microsoft. It has a number of versions, including including Foundation, Standard, Enterprise, Datacenter, Web, HPC Server, Itanium and Storage; new features included server core installation and Hyper-V.