IE 11 fails to start, Acrobat reader DC fails to update Windows 10 1607

for the first step try this,

Open an elevated Command Prompt (Press the Windows + X button at the same time, then choose Command Prompt (Admin))
Type the following command, and replace the "C" with your system drive letter ( if "C:" is not your Windows drive ): CHKDSK C: /F
Hit the enter key, Command Prompt will now start CHKDSK

check the event viewer ... logs...

Check services.msc, if some services fail to start then updates and installs will fail. Look especially for:

Adobe Acrobat Update Service (Automatic)
Adobe Genuine Software Integrity Service (Automatic)
Background Intelligent Transfer Service (Automatic)
Windows Installer (Manual)
Windows Update (Manual)

Here are a couple of errors in the application log
Log Name:      Application
Source:        Application Error
Date:          2017-03-04 10:28:04 AM
Event ID:      1000
Task Category: (100)
Level:         Error
Keywords:      Classic
User:          N/A
Computer:      DESKTOP-2R5PUM9
Description:
Faulting application name: iexplore.exe, version: 11.0.14393.0, time stamp: 0x57899953
Faulting module name: ntdll.dll, version: 10.0.14393.479, time stamp: 0x5825887f
Exception code: 0xc0000005
Fault offset: 0x0000000000075dd0
Faulting process id: 0x3680
Faulting application start time: 0x01d294fbea7ec51d
Faulting application path: C:\Program Files\Internet Explorer\iexplore.exe
Faulting module path: C:\WINDOWS\SYSTEM32\ntdll.dll
Report Id: 25a79154-5cb5-4798-83a6-cbbdc4e7252d
Faulting package full name:
Faulting package-relative application ID:
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
  <System>
    <Provider Name="Application Error" />
    <EventID Qualifiers="0">1000</EventID>
    <Level>2</Level>
    <Task>100</Task>
    <Keywords>0x80000000000000</Keywords>
    <TimeCreated SystemTime="2017-03-04T15:28:04.497644700Z" />
    <EventRecordID>12544</EventRecordID>
    <Channel>Application</Channel>
    <Computer>DESKTOP-2R5PUM9</Computer>
    <Security />
  </System>
  <EventData>
    <Data>iexplore.exe</Data>
    <Data>11.0.14393.0</Data>
    <Data>57899953</Data>
    <Data>ntdll.dll</Data>
    <Data>10.0.14393.479</Data>
    <Data>5825887f</Data>
    <Data>c0000005</Data>
    <Data>0000000000075dd0</Data>
    <Data>3680</Data>
    <Data>01d294fbea7ec51d</Data>
    <Data>C:\Program Files\Internet Explorer\iexplore.exe</Data>
    <Data>C:\WINDOWS\SYSTEM32\ntdll.dll</Data>
    <Data>25a79154-5cb5-4798-83a6-cbbdc4e7252d</Data>
    <Data>
    </Data>
    <Data>
    </Data>
  </EventData>
</Event>


In January this error started Event ID 1021
Product: Adobe Acrobat Reader DC - Update 'Adobe Acrobat Reader DC
 (15.016.20039)' could not be removed. Error code 1646. Windows Installer can create logs to help troubleshoot issues with installing software packages. Use the following link for instructions on turning on logging support

create a restore point,
Uninstall Windows Explorer from Windows features, Restart, then reinstall it from Windows features again and check if this solve the problem.
https://www.technipages.com/uninstall-ie11-windows-10

I checked the services, but there is no adobe services listed

I ran chkdsk and there was no change in the operation

I unchecked the IE 11, restarted, checked it restarted and no change

I uninstalled Malwarebytes and IE 11 worked,'

I re installed Malwarebytes and Malwarebytes is giving full protection, and IE 11 is working

The acrobat reader DC still will not uninstall or update - still indicates the patch cannot be uninstalled and gives an unknown error when trying to let Kaspersky do the update

I thank everyone, but this was the only solution that actually worked for my problems.

I'm glad I could help. Thanks