can I run any commands on one of the other exchange server in other siteIf I understand this question correctly you can make config changes on any CAS in the same organization. This is why most powershell commands that configure items on specific servers have a -server switch. An example of this is the New-MailboxDatabase cmdlet. This cmdlet requires you to specify the server you want the database on; it doesn't really care which server you are currently connected to.