Moving a windows 7 install to new hardware

I've had good luck with Paragon's Drive Copy to accomplish this.  You can boot it from a USB stick and then have it do an adequate enough job of setting up drivers that you'll be able to boot on the new motherboard.

Depending on how different the new motherboard is, this might not be necessary at all.

Of course, be careful about Windows licensing issues.  Depending on which type of Windows license you have, this may or not be in compliance.

It's a non-profit with (I believe) volume license on their PC's. The manager said the license was purchased separately, so not an OEM license. Would that be in compliance? I'll  pass the information along. Thanks

You should check with Microsoft's site ("I heard it on EE" will not hold much weight!) but I believe that with a volume license you can move it to different hardware.

OK thanks, I'll get in touch with his sales rep. What is EE?

the answer is simple no, it is not easy, you might have licensing problem also driver and controller problem.

more details:
https://www.howtogeek.com/239815/why-cant-you-move-a-windows-installation-to-another-computer/

CompProbSolv - EE is "Experts Exchange".  :)

Regarding your issue, if they're a non-profit with volume licensing, the license is not tied to any specific computer or hardware, so moving them around is not a big deal as long as you stay compliant with the number of licenses you have.  If Windows comes up and says it needs to be activated, just put in their volume license key again.

As far as moving to a new motherboard, you can just install the motherboard and then deal with whatever driver issues come up.

This isn't the same as dealing with an OEM or retail license... the license isn't tied to hardware at all.