Is there any advantage to using hybrid drives as data or backup drives?

The advantage is speed. Now how MUCH advantage is up for debate. Do I need hot/cold data for backups? Probably not. Data? Depends on the data.  There is no one right answer.

Speed is always an advantage. I was more concerned with whether or not there is any advantage given its use. Cache is generally advantageous when you have a program or data that is pulled into and out of memory often, not if the data is going to be written once. This would be useful to gamers because the saved games they are playing would be readily available.  I work with home and business customers that use their computers to do everyday work, not gamers and the only drives I'll put in these people's computers are SSDs or NVMEs.  I might use a 2T Firecuda as a backup or data drive, but I don't know if there's any advantage using them this way over a normal mechanical sata drive.

Thanks,
Alan