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Exchange 2016 Edge Transport: Transport Rules Error

We're seeing an issue on both of our Exchange 2016 Edge Transport errors where some transport rules will execute properly, however some won't. Regardless, whenever a transport rule is fired off, we see the below error. Has anyone seen this before? This is Exchange 2016 CU6.

By the way, we have Exchange installed on a separate drive. All the logs are installed on a separate drive as well (message tracking, protocol logging, etc).

Log Name:      Application
Source:        MSExchange Messaging Policies
Date:          9/13/2017 12:23:55 AM
Event ID:      4009
Task Category: Rules
Level:         Error
Keywords:      Classic
User:          N/A
Computer:      NYCIFXEXEDGE01.hbk.com
Description:
Transport engine failed to evaluate condition or apply action. The rule is configured to ignore errors. Details: 'Organization: '' Message ID '<CA+gBsVn9Afh+nj07nN+RjCM6ibYuuokBYRpT-SBVC07FLtkRRg@mail.gmail.com>' Rule ID 'f31b05d3-b846-4b4b-8d2b-7b105bfb4f2d' Predicate '' Action ''. FilteringServiceFailureException Error: Microsoft.Exchange.MessagingPolicies.Rules.FilteringServiceFailureException: FIPS text extraction failed with error: 'Retrieving the COM class factory for component with CLSID {C635C36E-6F37-4D3A-8005-3893029827D5} failed due to the following error: 80040154 Class not registered (Exception from HRESULT: 0x80040154 (REGDB_E_CLASSNOTREG)).'. See inner exception for details ---> System.Runtime.InteropServices.COMException: Retrieving the COM class factory for component with CLSID {C635C36E-6F37-4D3A-8005-3893029827D5} failed due to the following error: 80040154 Class not registered (Exception from HRESULT: 0x80040154 (REGDB_E_CLASSNOTREG)).
   at Microsoft.Filtering.SafeWorkSubmissionManager..ctor()
   at Microsoft.Filtering.FilteringService..ctor()
   at Microsoft.Exchange.MessagingPolicies.Rules.FilteringServiceFactory.Create(IFipsDataStreamFilteringService& filteringService)
   at Microsoft.Exchange.MessagingPolicies.Rules.UnifiedContentServiceInvoker.BeginTextExtraction(FilteringServiceInvokerRequest filteringServiceInvokerRequest, TextExtractionCompleteCallback textExtractionCompleteCallback)
   --- End of inner exception stack trace ---
   at Microsoft.Exchange.MessagingPolicies.Rules.UnifiedContentServiceInvoker.GetUnifiedContentResults(FilteringServiceInvokerRequest filteringServiceInvokerRequest)
   at Microsoft.Exchange.MessagingPolicies.Rules.MailMessage.GetUnifiedContentResults()
   at Microsoft.Exchange.MessagingPolicies.Rules.MailMessage.get_BodyContent()
   at Microsoft.Exchange.MessagingPolicies.Rules.MessageBodies.Microsoft.Exchange.MessagingPolicies.Rules.IContent.Matches(MultiMatcher matcher, RulesEvaluationContext context)
   at Microsoft.Exchange.MessagingPolicies.Rules.TextMatchingPredicate.OnEvaluate(RulesEvaluationContext context)
   at Microsoft.Exchange.MessagingPolicies.Rules.PredicateCondition.Evaluate(RulesEvaluationContext context)
   at Microsoft.Exchange.MessagingPolicies.Rules.OrCondition.Evaluate(RulesEvaluationContext context)
   at Microsoft.Exchange.MessagingPolicies.Rules.AndCondition.Evaluate(RulesEvaluationContext context)
   at Microsoft.Exchange.MessagingPolicies.Rules.RulesEvaluator.EvaluateCondition(Condition condition, RulesEvaluationContext evaluationContext)
   at Microsoft.Exchange.MessagingPolicies.Rules.TransportRulesEvaluator.EvaluateCondition(Condition condition, RulesEvaluationContext evaluationContext). Message-Id:<CA+gBsVn9Afh+nj07nN+RjCM6ibYuuokBYRpT-SBVC07FLtkRRg@mail.gmail.com>'
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Adam Brown
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Do you have any additional security software installed that would be scanning emails for things? The error you're getting is that a specific transport-agent isn't properly loaded. If you are using some scanning software (like GFI or Symantec's email security solutions) then I would look at those solutions and make sure they are properly installed and that the transport agents tied to them are registered correctly.
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Adam, thanks for your response.  I removed Trend Micro Deep Security but am seeing the same issue.  I tried creating a test address rewrite entry but am consistently seeing the same error after sending as batch of test messages.
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Resolved on own.