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As long as you don't need to replicate TB of data then dedupe and DFSR work well together.
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We do have TB's of data although not being replicated a lot I have seeded the drives. &nbsp;Lots of geology files and maps. &nbsp;On average maybe 100GB replication a day.
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2012 R2 is supposed to handle up to 100TB DFSR but I had troubles with 30 TB of moderate data change rate (50 - 100 GB/day) with DFSR and dedupe. I ended up using a robocopy job to move the data daily for this share. But I also have about 5TB on DFSR and dedupe that is running without issue. <br />
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That's some anecdotal evidence. Not sure sure what the common experience is.
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But you are using Dedupe right?
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Yup. These scenarios are using dedupe.
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Ok thanks and maybe I missed it but Dedupe on both ends?
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We have DFS shares on servers in remote offices, do if I turn on Dedupe on the main servers at corp should I turn it on at the remote DFS servers? &nbsp;Has anyone seen issues with Dedupe and DFS?<br />
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Thanks
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We have DFS shares on servers in remote offices, do if I turn on Dedupe on the main servers at corp should I turn it on at the remote DFS servers?  Has anyone seen issues with Dedupe and DFS?

Thanks

Windows 2012 R2 Dedupe and DFS shares

This topic area includes legacy versions of Windows prior to Windows 2000: Windows 3/3.1, Windows 95 and Windows 98, plus any other Windows-related versions including Windows Mobile.

Windows OS

Windows Server 2012 is the server version of Windows 8 and the successor to Windows Server 2008 R2. Windows Server 2012 is the first version of Windows Server to have no support for Itanium-based computers since Windows NT 4.0. Windows Server 2012, now in its second release (Windows Server 2012 Release 2) includes Foundation, Essentials, Standard and Datacenter, and does not support IA-32 or IA-64 processors.