Windows 10, Office 365(Outlook 2016) and Default mail app

I have just set up a new Windows 10 Pro workstation.  I have installed Office 365 (all apps), Sage 50 (our accounting software) and various other apps.  
Everything seemed to be working well until the user attempted to email an invoice to a customer using Sage.  We got an error message stating that there was no default email app installed.
I thought this was strange since the email had been working fine.  However when I looked at the "Default" apps in the settings, I saw that the default mail app was set to "Mail".   "Outlook 2016" was in the drop down list but when I try to change the default it won't change from "Mail".  
I have changed the user from "user" to "local administrator" with no change.  I have deleted the account and rebuilt with a new profile with no luck.

I'm really kind of stuck as this is a strange problem and other then deleting Office 365 and reinstalling I'm at a dead end.
Any ideas would be appreciated.

Ken GraserIT ManagerAsked:
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JohnBusiness Consultant (Owner)Commented:
Windows 10, Start, Settings, Apps, Default Apps and ensure in there Outlook 2016 is default.

See if that helps and if not, and all you have done, it may be a Sage problem. Contact Sage Support.
Tom CieslikIT EngineerCommented:
When you change Default Mail application to Outlook under App/Default Apps windows can ask you are you sure want to change default application and try to convict you to use Mail (same when you trying switch default browser to Chrome)

Many people complain that Outlook is not accepted by Windows 10 to set as default.
It's strange since Office (Outlook) and Windows has same owner (Microsoft)

You can find step by step how to work around in link below. This steps are starting from conventional method then is going through registry if Windows think that is a Master of Universe :) LOL

Here is your link

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Jackie ManIT ManagerCommented:
Have you installed MS Office 2016 64 bit?

If yes, uninstall it and install MS Office 2016 32 bit and you need to do the registry change if the OS is 64 bit.

Sage 50 will only work with MS Outlook 2016 32 bit.

"The fix, in all cases, was to add this registry key:

Windows Registry Editor Version 5.00
[HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Microsoft\Windows Messaging Subsystem]


Sage 50 Canadian uses the key above to know whether MAPI is installed.   If the key isn't there, even if MAPI is perfectly ready to go, Sage 50 can't 'see' it.   On 64 bit OS Sage 50 uses MAPI32.DLL in c:\windows\sysWOW64 to send email through Outlook, and it definitely works with Outlook 2016.  (but not with the online 'cloud' browser-ey one, nothing works with that).

I hope that helps, if you're not running a 64 bit operating system, then the above is not the issue / fix."

Ken GraserIT ManagerAuthor Commented:
Thanks for all the suggestions.  None of them worked however.  I did solve the problem by rebuilding the user profile.  I can't tell you why that worked but it did so I'll take it and move on.

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