Hello! I made a big mistake by changing the permissions to a registry key:
HKEY_Current_USER -> Software -> Microsoft -> Internet Explorer -> Main
Doing this has caused IE to not open.
I denied permissions to SYSTEM and maybe even ADMINISTRATORS and now I am unable to change them back. I get an error that says it cannot open MAIN due to access denied and when I try to change ownership, it won't allow me to make the change.