Possible Deduplication Issue on File Server

We have a Windows Server 2012 R2 File Server with deduplication enabled.  Last week, our Veeam replication job for this server began taking very long (hourly job taking 2-3 hours to complete).  Our other file server with deduplication enabled is not experiencing this issue.

While investigating, the only difference that I found was that the server with the issue has a number of Dedup files that are sitting near the top of the Disk I/O listing (see attachment).  The files are being written to, but no dedup jobs are currently running.  These files are not listed in the Process Manager of the file server not experiencing the slow replication.

Is there a way to clear these files from the server, or am I looking at the wrong thing?
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Brian BEE Topic Advisor, Independant Technology ProfessionalCommented:
I had thought the Veeam backup stores are already deduplicated. So I don't think there would be any value in deduplicating them at the file level.

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Thomas RushCommented:
Brian B is right -- a properly deduplicated data stream will see very little improvement from a second deduplication pass (that said, if your first pass was file granularity or fixed-block dedupe, you might see some significant dedupe on the second pass -- HP showed that this could happen when a Veeam (fixed-block dedupe) stream was sent to a StoreOnce appliance (variable block).
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