Suddenly can't reach web URLs through Outlook 2016 links in emails - Windows 10

On some computers we suddenly can't reach web URLs through Outlook 2016 links in emails - Windows 10.

The error message seems to be well-known:
"Your organization's policies are preventing us from completing this action for you.  For more info, please contact your help desk."
Well, of course, I am the help desk!  
I have followed all the steps in

Now, I don't want to get off onto a tangent here but just for completeness:
The User is accessing his .pst file over the network.. :-(
But, the problem remains on the computer where the file is located.
Any computer accessing the file seems to have the same problem.
So, I'd suggest we just focus on the computer that has the file, eh?
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Fred MarshallPrincipalAsked:
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This is pop and not imap ,right?
Have you tried creating a new user profile and recreating the pst local?
SeanSystem EngineerCommented:
Are you the admin for exchange? It's possible that there has been a policy added to block hyperlinks in exchange.
Fred MarshallPrincipalAuthor Commented:
There is no Exchange involved.  If there were, wouldn't we be talking about .ost files?
email is received via POP but I'm not sure that this part should matter.
There is a firewall at the facility but other computers don't have the problem.  So that lets out the firewall blocking the web accesses when the links are clicked.
It all *seems* to point to the .pst file which is much different than the "solutions" in the link I provided.
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Have you tried repairing the networked pst with scanpst?
One of reasons why pst over a network share is flaky is because it's very easy to corrupt it.
Fred MarshallPrincipalAuthor Commented:
pgm554:  You didn't notice my unhappy face?

ALL:  We created an all-new .pst file and the same issue remains.
Fred MarshallPrincipalAuthor Commented:
We recreated the email profile getting a new .pst.  It did no good.
No new Windows User profile was done (yet).
NB:  This applies to 2 computers at 2 sites (that is, if a computer is moved from one site to another).  
So, it's not site-specific nor computer-specific.

Suddenly, the problem went away today, just as quickly as it appeared.
I guess now we'll never know.
Fred MarshallPrincipalAuthor Commented:
I did do some more research and found this:

It talks about browser invovlement.  When you think about it, this makes sense.  
Outlook does its job.
The link has to cause a browser to open, which, shall we say, it does.
Then the browser has to open the link.
So, if it doesn't open the link, the problem appears to be more likely with the browser.
Fred MarshallPrincipalAuthor Commented:
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