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There is no such thing as Exchange 2018 CU8, you probably mean Exchange 2016 CU8?
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Are you trying to install a completely separate Skype organization in the same AD organization? this is not supported. You need to just create a new pool for the separate site, Even if that new Pool only has a Standard server in it.
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i created new pool with new topology &nbsp;but getting this error
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thanks &nbsp;for your suggestion, will try this tomorrow &amp;&nbsp;let you know &nbsp;the result
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Thanks lvjeff for you info,<br />
<br />
I was able to install Skype for business &nbsp;in other two sites. but i just want to know something,<br />
<br />
we have five sites &nbsp;for skype for Business 2015. but &nbsp;in third site i have install skype for business firstly &nbsp;and this third site has become a central Management store means main site. is it possible to make my first site as main site or remove &amp;&nbsp;re-install the all skype for business.
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Since each site has its own SQL server, you can place the Central Management store in any of them. Open a Skype Management Shell and run the command Install-csDatabase -CentralManagementDatabase<wbr /> -SQLServerfqdn &lt;FQDN of the server in the pool (site) you want to host Central Management&gt;. This assumes you are using the default instance for the SQL server. If you are using a named instance, add the switch -SQLInstanceName &lt;name&gt; to the command. This will install an empty Central Management Database in the pool(site) you selected. &nbsp;Then run enable-cstoopology. Last &nbsp;thing to do is wait a few and run get-csmanagementStoreRepli<wbr />cationStat<wbr />us to make sure you are up to date on all servers. then run Move-CsManamgementServer. this assumes you only have the Central Management Database installed in the current pool and the one you want to move to. Once the move is made, wait a bit and verify things by rerunning get-csmanagementStoreRepli<wbr />cationStat<wbr />us. Lastly, if everything looks good, You should remove the old Central management store. Uninstall-CsDatabase -CentralManagementDatabase<wbr /> -SqlServerFqdn &lt;FQDN of the old SQL Server&gt; -SqlInstanceName &lt;if needed&gt;
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Thanks for you help, really appreciated.<br />
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Just to know one last this.. there is DR site in these sites.. can you please help &nbsp;to make DR site for skype. means all the pool will be replicate to DR site
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Thanks Lvjeff for your help ..!
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<div class="content wysiwyg-content">
Dear all<br />
<br />
we have 5 AD site , where we have install Exchange 2016 CU8, one of the site i have already installed Skype for business 2015 without any issue . <br />
When i am installing an skype for business in another site getting an error while publishing an topology. <br />
<br />
<a href="https://filedb.experts-exchange.com/incoming/2018/01_w03/1219538/Skype-error.JPG" target="_blank" title="Skype-error.JPG (35 KB)"><img alt="Skype-error.JPG" class="file-block lazyload" style="max-width: 597px;" data-src="https://filedb.experts-exchange.com/incoming/2018/01_w03/1219538/Skype-error.JPG" /></a><a href="https://filedb.experts-exchange.com/incoming/2018/01_w03/1219537/Skype-error.JPG" target="_blank" class="file-inline" title="Skype-error.JPG (35 KB)"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path d="M67.508 468.467c-58.005-58.013-58.016-151.92 0-209.943l225.011-225.04c44.643-44.645 117.279-44.645 161.92 0 44.743 44.749 44.753 117.186 0 161.944l-189.465 189.49c-31.41 31.413-82.518 31.412-113.926.001-31.479-31.482-31.49-82.453 0-113.944L311.51 110.491c4.687-4.687 12.286-4.687 16.972 0l16.967 16.971c4.685 4.686 4.685 12.283 0 16.969L184.983 304.917c-12.724 12.724-12.73 33.328 0 46.058 12.696 12.697 33.356 12.699 46.054-.001l189.465-189.489c25.987-25.989 25.994-68.06.001-94.056-25.931-25.934-68.119-25.932-94.049 0l-225.01 225.039c-39.249 39.252-39.258 102.795-.001 142.057 39.285 39.29 102.885 39.287 142.162-.028A739446.174 739446.174 0 0 1 439.497 238.49c4.686-4.687 12.282-4.684 16.969.004l16.967 16.971c4.685 4.686 4.689 12.279.004 16.965a755654.128 755654.128 0 0 0-195.881 195.996c-58.034 58.092-152.004 58.093-210.048.041z"/></svg>Skype-error.JPG</a>
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Skype-error.JPG

Dear all

we have 5 AD site , where we have install Exchange 2016 CU8, one of the site i have already installed Skype for business 2015 without any issue . 
When i am installing an skype for business in another site getting an error while publishing an topology. 



MUltisite Skype for Business 2015 installation error

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.

Exchange

Installation is the act of making a computer program program ready for execution. Because the process varies programs often come with a specialized program responsible for doing whatever is needed for their installation. Installation may be part of a larger software deployment process. Cross platform installer builders that produce installers for Windows, Mac OS X and Linux include InstallAnywhere, InstallBuilder and Install4J. Installers for Microsoft Windows include Windows Installer, InstallShield, and Wise Installation Studio; free installer-authoring tools include NSIS, IzPack, Clickteam, InnoSetup, InstallSimple and WiX. Mac OS X includes Installer, and also includes a separate software updating application.

Installation

Skype is for doing things together, whenever you’re apart. Skype’s text, voice and video make it simple to share experiences with the people that matter to you, wherever they are.

With Skype, you can share a story, celebrate a birthday, learn a language, hold a meeting, work with colleagues – just about anything you need to do together every day. You can use Skype on whatever works best for you - on your phone or computer or a TV with Skype on it. It is free to start using Skype - to speak, see and instant message other people on Skype for example.