I have an issue which is getting worse, about six months ago we deployed a Windows 2016 RDP Server for approx 20 users, the Server is hosted on an ESXI system and the Server provides desktop access to their main application and office 2016 which includes Outlook 2016 with Exchange accounts to an offsite, Exchange Server in the cloud hosted by another company.
Some RDP profiles have the same Exchange accounts so a number of users will send receive using the same email account. Recently users have been experiencing a prolonged period when openening Outlook and for some users Outlook will fail to open and will complain that its unable to access the folders, if I "taskkill" all the outlook processes on the Server it will allow everyone to connect to their mailboxes. Also when this issue occurs I can always OWA into the same email account from the RDP desktop so the hosted Exchange Server is still accepting connections. My gut feeling is that the issue maybe because all profiles are running in "online" mode which is default for RDP Servers, but its causing performance issues because the Exchange Server is offsite. I'm considering changing some of the shared accounts to "cached mode" to see if this alleviates some of the burden, any suggestions please?