Windows Server 2016 Standard 4Kn drives - application compatibility

Windows Server 2016 Standard supports 4Kn drives. Does this mean any software that supports Windows Server 2016 Standard will work on 4Kn drives?

System Requirements: Sage 300 Construction and Real Estate 17.1
https://support.na.sage.com/selfservice/viewContent.do?externalId=81067&sliceId=1

Sage does not mention if 4Kn drives are supported or not. How does one determine if software programs are compatibility with 4Kn drives?
Member_2_6428635Asked:
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Cliff GaliherCommented:
In general yes.  There can always be the oddball exception, but it'd usually deal under programs that *nees* low level disk access. Data recovery programs, some non-standard antivirus programs. Backup programs that try to do direct block level monitoring or copying. Your standard LOB apps would rarely if ever know the type of disk being used.
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arnoldCommented:
As Cliff pointed out, most software is oblivious to the underlying storage system that is handled by the OS kernel.

Application that require raw access to storage include info on storage as a requirement in the specs and best practices.
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