USB Mouse/Keyboard not working Windows 10

USB mouse and keyboard have stopped working.  Everything was fine mid-afternoon yesterday, and a few hours later they didn't work.This is a Dell Lattitude 6400 running Windows 10 64 bit, with an external USB mouse and keyboard. I have ruled out the obvious - tested mouse and keyboard on another machine and they work fine. Rebooted, no change.  Updated all drivers, no change.  The mouse is recognized as a USB Optical Mouse when I plug it in, but when I go to Device Manager it is listed under "Other" (not under Mice and Pointing Devices) and when I check properties it says it has no driver. I try to update the driver, but no driver is found. Tried restoring to a previous restore point, no change. However, if I go into the BIOS setup, the optical mouse works fine. Also, when I booted from a Windows10 install disk, the optical mouse also worked fine. Since there doesn't seem to be an actual mouse driver (just built into Windows) I'm at a loss.  I REALLY don't want to reinstall windows and lose all the apps already installed.  Any ideas? Please? Thanks in advance!
dkreinesAsked:
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Joe Winograd, Fellow&MVEDeveloperCommented:
Following up on originalhandyandy's comment, there's a good discussion of the issue here:

Report of the Win10 1709 cumulative update KB 4074588 disabling USB devices

Regards, Joe
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HELFITCommented:
This is our workaround for now:

Go to device manager -> Other Devices

Find the non-functioning device (it should have an ! on it) Update Driver - Browse local computer for the driver. Folder location is %windir%\WinSxS. If there are multiple listings of the disabled device, you may have to repeat this for each one. Reboot.

If you change ports you may have to do this again - this is only a workaround - not sure which MS update broke it but would like to know...
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Joe Winograd, Fellow&MVEDeveloperCommented:
not sure which MS update broke it but would like to know...
According to numerous posts on the web, it is update KB4074588, although I can't personally confirm that.
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HELFITCommented:
Yes, we've also had success with uninstalling KB4074588, reboot, and reinstalling the update.
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Joe Winograd, Fellow&MVEDeveloperCommented:
we've also had success with uninstalling KB4074588, reboot, and reinstalling the update
Thanks for confirming that, Helfit — very helpful! Regards, Joe
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techplusCommented:
I've had this happen with several of my clients' computers since last Thursday afternoon. No real pattern to it, different types of computers, some lose only mouse, some keyboard and mouse, and some other USB devices like scanners. It's definitely KB4074588. Fortunately, I have remote software on each so I've been able to remote in and uninstall KB4074588. To get them going faster, I've been able to disable and re-enable the mouse and keyboard after the update has been uninstalled, and that gets them back going. Then when they're done for the day I have gone in and restarted the computer and reinstalled KB4074588 and it appears to work fine after that, even after multiple reboots. If you don't have remote software to get in to uninstall it, you should be able to uninstall it from the Recovery Console with the DISM command, but I haven't tried that yet. You should be able to find how to uninstall from the command prompt in Recovery Console with the DISM command online.
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dkreinesAuthor Commented:
Yes, it was KB4074588. Once that was uninstalled everything returned to normal. I am guessing Microsoft no longer tests their software!
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dkreinesAuthor Commented:
Thanks for the help!
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Joe Winograd, Fellow&MVEDeveloperCommented:
You're welcome — happy to help!
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D ReidCommented:
I have the same problem, both mouse and keyboard stopped working.  the proposed fixes here sound good, but how do u do any of this with not mouse or keyboard?
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HandyAndy GoodmanCC&BWCommented:
If you remote into the computer the remote mouse and keyboard work fine. I just did this today via LogMeIn but have every reason to believe it will also work via rdp.
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D ReidCommented:
I’m unable to access remotely.   I’m not the best at this but I don’t know how I would get in now without having set something up prior?
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HandyAndy GoodmanCC&BWCommented:
if you have another computer on the same network, you would enter rpd in the search box then use the credentials of a user on the broken box to log onto it remotley
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D ReidCommented:
I will see if I can do that. thanks
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einsteinqCommented:
Here's how you remove this update if you don't have the ability to remote into the computer:
Turn the computer off, and as soon as the vendor logo disappears, hold the power button down until it powers off.
Do this twice, on the third boot up, it should say "Preparing automatic repair" if it doesn't, you're powering off a bit too soon. Try again until you see that message, followd by "Diagnosing your PC"
Click "Advanced Options" to enter enter recovery console
Once you see the blue screen, you need to launch a CMD prompt. When you get to the CMD prompt, type the following:
wusa /uninstall /kb:4074588
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Paul PaulCommented:
Also if you have PS/2 port in your motherboard, you can connect PS/2 mouse or keyboard. It works too.
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