Windows 10 Updates caused USB wired keyboard and mouse to stop working

Windows 10 Updates caused USB wired keyboard and mouse to stop working on two workstations. I was able to remote into both workstation via RDP and LogMeIn and troubleshoot. Removed all USB hubs from device manager, rebooted, issue still persists. Booted to safe mode and still not working. Booted to BIOS and mouse and keyboard do work. Attempted restore point but both machines don't have any. Device manager shows the drivers for the keyboard and mouse wasn't installed.
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YortAsked:
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Joe Winograd, Fellow&MVEDeveloperCommented:
Hi Yort,

The answer is probably in this recent EE thread:

https://www.experts-exchange.com/questions/29084840/USB-Mouse-Keyboard-not-working-Windows-10.html

Your problem sounds the same or, at least, similar. Regards, Joe
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JohnBusiness Consultant (Owner)Commented:
Go back to Safe Mode and see if you can Restore to a Prior point before the recent updates. Restore is in System Properties. A bunch of machines (mostly Dell that I saw) have had this issue.
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YortAuthor Commented:
@JohnHurst...thank you for your quick reply. I booted to safe mode but the keyboard and mouse still don't work. I have hard shutdown the system but it still boots back to safe mode, thus, I am stuck at this point.
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JohnBusiness Consultant (Owner)Commented:
If the machine simply will not start, you need to remove the drive, recover data from it, get the Vendor Recovery Media and reinstall Windows 10.

You can try the USB Key from the Media Creation Link but the vendor USB is better.

https://www.microsoft.com/en-us/software-download/windows10
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YortAuthor Commented:
@JohnHurst...thanks...that's where I figured I was at. I was hoping someone had come across a fix that a vendor put out. Thanks!!!
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JohnBusiness Consultant (Owner)Commented:
You can try getting a BIOS update on bootable USB key from your computer manufacturer and updating BIOS. No guarantee that this will work.

With respect to reinstalling Windows, if you cannot start at all (normal or safe) then that is what you need to do.
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YortAuthor Commented:
@Joe_Winograd - thank you very much...this saved my time and sanity.
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Joe Winograd, Fellow&MVEDeveloperCommented:
You're very welcome, Yort — I'm glad that worked for you. Regards, Joe
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