Keyboard and mouse don't work

I have an ASUS desktop running windows 10 home. The mouse and keyboard don't work when windows boots up. Tested keyboard and mouse on other pc and it worked fine. used every usb port on the problem machine and still nothing. Attempted to use a ps/2 mouse and the same issue is happening. Steps taken:

1. booted into bios, keyboard works. made sure usb ports were enabled
2. rebooted still didn't work.
3. booted into safe mode and they still don't work.
4. attempted system restore but no restore points are available.
5. had to go into command prompt start up and enable ps/2 mouse, disabled and enabled usb ports .
6. booted into safe mode and ps/2 mouse works but still no usb.
7. attempted to update drivers on mouse and keyboard, but says windows was unable to install the driver.
8. Manually downloaded drivers onto flashdrive from other pc and still couldn't install the drivers.

Wired Mouse and Keyboard are both Asus, also tried Wired Dell mouse and keyboard.
Any ideas?
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Jason JohanknechtIT ManagerCommented:
Yes, this problem is growing.  I have one, and I cannot get it to remove the pending action yet.  What CPU do you have?  Trying to collect more info to help on my issue.
Jason JohanknechtIT ManagerCommented:
The DISM command returns:
This version of %1 is not compatible with the version of windows your running....  (64-bit is the OS).
Error: 216

The CPU is an i3-2120.  HP Touchsmart 420.  Windows 10 Pro 64-bit
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ebsadminAuthor Commented:
I saw the windows update solution before hand and attempted to remove it but my pc locks up and won't remove the update. Can't kill it in task manager either. Sorry I didn't include this. It finally removed it but still have the same issue.
Jason JohanknechtIT ManagerCommented:
Do you have the input.inf file in windows\INF folder?
ebsadminAuthor Commented:
The problem overall was the update. I deleted the update initially, but when it restarted the update was still there after looking. I then checked to see if any antivirus was running and nothing was. reactivated Norton and ran a virus scan in safe mode and it removed a virus and had no problems deleting the update afterwards. restarted and everything is working now. Thank you.
Joe Winograd, Fellow&MVEDeveloperCommented:
> reactivated Norton and ran a virus scan in safe mode and it removed a virus and had no problems deleting the update afterward

That's an interesting twist! Thanks for letting us know.

> restarted and everything is working now. Thank you.

You're welcome. Very glad to hear that. Regards, Joe
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