400.4.4.7 in 2013 exchange

Thanks for reply me.
I have contacted to remote domain and as per them they are receiving rest of the emails as normal.
So they are asking to check in our end. But we can’t send to this specific domain.

Post the full message you are receiving in return.

From: Microsoft Outlook <xxxxxxxxxxxxx>
Date:
To: <xxxxxxx>
Subject: Undeliverable: RE:

Delivery has failed to these recipients or groups:xxxxxxx

recipient  mail ID (recipient  mail ID)
The server has tried to deliver this message, without success, and has stopped trying. Please try sending this message again. If the problem continues, contact your helpdesk.

recipient  mail ID (recipient  mail ID)
The server has tried to deliver this message, without success, and has stopped trying. Please try sending this message again. If the problem continues, contact your helpdesk.

Diagnostic information for administrators:

Generating server: our server name
Total retry attempts: 190

recipient  mail ID
Remote Server returned '550 4.4.7 QUEUE.Expired; message expired'

recipient  mail ID
Remote Server returned '550 4.4.7 QUEUE.Expired; message expired'

Original message headers:

Received: from our server (mail server IP) by our server
(mail server IP) with Microsoft SMTP Server (TLS) id 15.0.847.32;  
Received: from our server ([]) by
our server ([fe80::9ce277:30a9%12]) with mapi id
15.00.0847.030;
From: xxxxx <xxxxxxx>
To: "xxxxx" <xxxxxxx>
CC: "xxxxxxxx" <xxxxxxxxx>,


Subject: RE:
Thread-Topic:
Thread-Index: AdOpgB9YlbLU4+prQDK2pExbylDK2QBpATBw
Date:
Message-ID: <our server>
Accept-Language: en-US
Content-Language: en-US
X-MS-Has-Attach: yes
X-MS-TNEF-Correlator:
x-originating-ip: ]
Content-Type: multipart/related;
boundary="_008_d428588_";
type="multipart/alternative"
MIME-Version: 1.0

After queue expired i am getting this message.

Unfortunately, the messages will expire after 48-72 hours if the recipients server does not respond.  It's still an issue with the receiving server.  Work with them.  Don't take their word for it.

I will inform them . Thank you for supporting me

Sufficient guidance provided for resolution.

Hi, when i tried to send email to one domain, its getting bounce back with error like  remote server returned 553. I have checked my domain and static IP in blacklist, its not in blacklist. And i have check my both domain and IP in https://www.spamhaus.org/pbl/ but its not listed there.
So can someone help me to sort out this.  Bounce back mail i copied below for reference.

 From: Microsoft Outlook
Sent: Thursday, April 12, 2018 9:45 AM
To: our ID
Subject: xxxxxxx
server-15.tower-184.messagelabs.com rejected your message to the following email addresses:
'recipient name.' (recipient  ID)
server-15.tower-184.messagelabs.com gave this error:
you are trying to use me [server-15.tower-184.messagelab s.com] as a relay, but I have not been configured to let you [My static IP, my domain] do this. Please visit www.symanteccloud.com/troubleshooting (http://www.symanteccloud.com/troubleshooting) for more details about this error message and instructions to resolve this issue. (#5.7.1)
A problem occurred while delivering this message to this email address. Try sending this message again. If the problem continues, please contact your helpdesk.
Diagnostic information for administrators:
Generating server: My mail server name
recipient email ID
server-15.tower-184.messagelabs.com
Remote Server returned '553-you are trying to use me [server-15.tower-184.messagelab 553-s.com] as a relay, but I have not been configured to 553-let you [My static IP, my domain ] do this. 553-Please visit www.symanteccloud.com/troubleshooting (http://www.symanteccloud.com/troubleshooting) for 553-more details about this error message and instructions 553 to resolve this issue. (#5.7.1)'
Original message headers:
Received: from My mail server name (my mail server IP) by My mail server name
((my mail server IP) with Microsoft SMTP Server (TLS) id 15.0.847.32; Thu, 12 Apr
2018 09:44:54 +0400
Received: from (my mail server name  ([IPv6 address]) by
(my mail server name ([IPV6 address ]) with mapi id
15.00.0847.030; Thu, 12 Apr 2018 09:44:54 +0400
From My email iD:  <My email iD>
To: 'recipient name .' <recipient  ID>
Subject: xxxxxx
Thread-Topic: my message subect
Thread-Index: AdPSIMxv4GBODkMLRzOp02tbWftk+A==
Date: Thu, 12 Apr 2018 05:44:53 +0000
Message-ID: <13c5077ff6e54c98be63c1ed7d740el>
Accept-Language: en-US
Content-Language: en-US
X-MS-Has-Attach: yes
X-MS-TNEF-Correlator:
x-originating-ip: [192.168.1.1]
Content-Type: multipart/related;
boundary="_004_13c5077ff6e54c98be63c1ed";
type="multipart/alternative"
MIME-Version: 1.0