Need to remove Network Proxy settings in IE transparent to all users

I need to (transparent to users) remove the check for (Win7 Pro and Win10 Pro) Internet Options>Connections tab>LAN Settings "Use automatic configuration script" for all users - to stop using a proxy URL - as an outgoing web security product does NOT uncheck this upon uninstall. If left there, all internet will fail after SW uninstall.

I can't use just GPOs as many remote/vpn users won't process GPOs before connection (using SBL (Startup Before Logon) isn’t an option for other reasons). I tried usin deployment software to (batch script) locally copy a reg fix that clears the AutoConfigURL key upon startup-but this fix doesnt always work, normally it doesn't (copies to startup folder for all users and executes on logon):

reg add "HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings" /v AutoConfigURL /t REG_SZ /d "" /f

I also saw a DefaultConnectionSettings reg key fix - to flip the 9th binary bit to remove the check - but not all systems have this binary entry in registry - and i dont want to introduce a key to Win7/Win10 laptops that don't have it, dont know what it would effect would have on users that don't have it, etc.

What else can I try/reg key can I manipulate to remove the check mark other than Group Policy?
Jody DavisSystems EngineerAsked:
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GPO refresh will occur automatically after 90 minutes, so even when not connected at logon, at latest, 90 minutes after VPN-connection, the key would be set if you use a group policy preference registry item to deploy it.

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Jody DavisSystems EngineerAuthor Commented:
thanks for the comment. while the answer isn't necessarily incorrect, a vpn user (after rebooting due to software install) is no longer on vpn/domain network - and group policy will not apply until it's once again connected to the network. this is strictly a vpn user issue i'm trying to solve that happens immediately, and as a reboot disconnects from the network (and can't use SBL), this won't fix this particular issue.

we're going to go ahead and just have them reconnect to  vpn (which will eventually correct the setting) and tell them also if you need it immediately, goto the settings and remove the check.

thanks for your help.
Jody DavisSystems EngineerAuthor Commented:
was an appropriate answer, but there are some circumstances that effect the solution - and as i'm going with a different approach, i'll just close the issue. good answer, though. dont get me wrong. thanks.
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Windows 10

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