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You could try disabling snapshots for the disk you do not want to snapshot by changing disk persistence <br />
<br />
But that may abort the entire snapshot process<br />
<br />
And why?
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You could try disabling snapshots for the disk you do not want to snapshot by changing disk persistence

But that may abort the entire snapshot process

And why?

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See here also valid for 6.x<br />
<br />
<a href="https://pubs.vmware.com/vsphere-50/index.jsp?topic=%2Fcom.vmware.vsphere.vm_admin.doc_50%2FGUID-8B6174E6-36A8-42DA-ACF7-0DA4D8C5B084.html" rel="ugc nofollow">https://pubs.vmware.com/vsphere-50/index.jsp?topic=%2Fcom.vmware.vsphere.vm_admin.doc_50%2FGUID-8B6174E6-36A8-42DA-ACF7-0DA4D8C5B084.html</a>
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See here also valid for 6.x

https://pubs.vmware.com/vsphere-50/index.jsp?topic=%2Fcom.vmware.vsphere.vm_admin.doc_50%2FGUID-8B6174E6-36A8-42DA-ACF7-0DA4D8C5B084.html [https://pubs.vmware.com/vsphere-50/index.jsp?topic=%2Fcom.vmware.vsphere.vm_admin.doc_50%2FGUID-8B6174E6-36A8-42DA-ACF7-0DA4D8C5B084.html]

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I took a look at the Modes: &nbsp;Independent - Persistent and Independent Non-Persistent. &nbsp;<br />
It tells me to select One of them. <br />
Which one should I select to Disable SnapShot from that disk and ensure there are no issues. &nbsp;OR I can select any?<br />
Thanks.
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I took a look at the Modes:  Independent - Persistent and Independent Non-Persistent.  
It tells me to select One of them.
Which one should I select to Disable SnapShot from that disk and ensure there are no issues.  OR I can select any?
Thanks.

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How can I take snapshots in vSphere 6.x of individual Hard Disks in a Multi Disk server
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How can I take snapshots in vSphere 6.x of individual Hard Disks in a Multi Disk server

How to take SnapShot of one Hard Disk in a Multi Disk Server in VMware

VMware, a software company founded in 1998,  was one of the first commercially successful companies to offer x86 virtualization. The storage company EMC purchased VMware in 1994. Dell Technologies acquired EMC in 2016. VMware’s parent company is now Dell Technologies.

VMware has many software products that run on desktops, Microsoft Windows, Linux, and macOS, which allows the virtualizing of the x86 architecture.  Its enterprise software hypervisor for servers, VMware vSphere Hypervisor (ESXi), is a bare-metal hypervisor that runs directly on the server hardware and does not require an additional underlying operating system.