share out a folder on a computer that is on a different subnet

I have a computer I want to transfer files to periodically and the computer is on a different subnet.  The source file backup computer is on the 192.168... network in the office and the file destiantion computer is on the  I have shared out a folder on the destiantion computer and I have a daily backup program on the source computer that I want to point to the destiantion computer and backup files to.  When I do a run - \\name (or IP, 172.16...) of destination computer I get the inaccessible message.  Do not have permission.  How can I get this to work?

This is a windows 2008 R2 Network environment
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Jeff GloverSr. Systems AdministratorCommented:
Well, there are several things to check. First, make sure there is a router between the two subnets. Can you Ping the destination computer from the source? Next, make sure the Firewall on the destination computer is either off or has an exception for File sharing. Also make sure the Firewall or router is not blocking you. Make sure the share you are targeting on the destination computer has the proper Share and NTFS permissions. To see the share, you just need read but to transfer files, you will need, at a minimum, Modify Share permission and Read, Read and Execute, List folder contents and Write NTFS permission. You really only need Write but the other 3 are the defaults for read permission.
  To help troubleshoot, you can use Ping and maybe even telnet client. You can use Telnet to see if a port is open. telnet <destination IP> 445. 445 is the SMB (File and print sharing) port Microsoft uses.
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