We are having an issue with Offline Folders disconnecting when saving from Office 365 2016 products. I'll use Word 2016 as the example. Word is version 1708 Build 8431.2250, Windows 10 pro is the OS, Version 1709 build 16299.431 Server is 2008r2 all updates. This seems to have started with April's Office updates.
Steps to reproduce: Open an explorer window to a location set to "always available offline", then open an existing word doc or create a new word doc an save it to the same Offline Folder synced with Sync Center that you opened in explorer, you should see the status go to offline. I've been able to reproduce this at will on multiple computers. The folder will automatically go back online in a few minutes.
I am able to drag and drop to the offline folder with no issues, and I am able to save from Adobe Acrobat Pro and Bluebeam among others with no issue. I only have a problem with Microsoft Office products.
Any help is appreciated.