I applied the 2018-05 Security and Quality Rollup for .NET Framework 3.5 - 4.7.1 (KB4099635) and now my outlook 2013 clients cannot connect to my exchange 2016 server. The outlook clients take forever (about 5 minutes) to load (Loading profile). Once up, all exchange folders are in the status "This folder has not yet been updated" "Trying to Connect" "Disconnected". When I restore the system state to last night's backup, it works. Unfortunately, windows automatically reinstalled the update and it quit working again.
How do I go about troubleshooting this problem? I dont see any problems in the event log, though there could be and I dont recognize their importance. I found a Health Checker script and ran it. It says I'm on .NET 4.7.1 and the maximum is 4.5.2.
Note: I started the outlook clients in safe mode, same problem.