Whenever I save my file on Photoshop CC, my artboard turns upside down. I use a Macbook which is hooked up to two other monitors and this seems to happen when I disconnect it from the monitors (when I need to work elsewhere), then
reconnect it to the monitors (when I'm back at my desk). I presume it's some resolution issue. The issue happens when my Macbook is reconnected to my two monitors. When I use my Macbook on its own, it doesn't happen.
What fixes it is minimizing and expanding the Photoshop program but the fix is temporary and the next time I save the file, it turns upside down again. A better fix is restarting Photoshop altogether, but the next time I disconnect/reconnect my Macbook to the monitors, it happens again.