550 5.7.1 Unable to relay Exchange 2013

Exchange 2013
Outlook 2013/2016

550 5.7.1 Unable to relay on mails to certain recipients

Is there anything i need to look at on exchange server

Microsoft remote connectivity analyzer, all test passed OK

Thanks in advance

Cian DevAsked:
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Tom CieslikIT EngineerCommented:
Double check your sent connectors, make sure you have created your own connectors and disabled or removed default one. Make sure you're using your MX record in send connector and good idea is to implement DKIM in your DNS

Also read this - it can help

Cian DevAuthor Commented:
The Recipient server was rejecting mail

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