the data received for the graph is as under  "OBX|32|ED|15000^WBC Histogram. Binary^99MRC||^Application^Octer-stream^Base64^AAAAAAAAAAAAAAABAgQHDRcmO1Z3nMPg9P/98+HKsZl8aFdGMyUfHBwcHR8iJy02QUpLTU5PT09P

Public Function ConvertBase64ToByteArray(base64 As String) As Byte()
    Return Convert.FromBase64String(base64) 'Convert the base64 back to byte array.
End Function

Private Function convertbytetoimage(ByVal BA As Byte())
    Dim ms As MemoryStream = New MemoryStream(BA)
    Dim image = System.Drawing.Image.FromStream(ms)
    Return image
End Function

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Public Class OBXGraph
    Inherits PictureBox

    Private pts As New List(Of Point)
    Private count, m As Integer

    Public Sub Draw(b64 As String)
        Dim idx = b64.IndexOf("Octer-stream^Base64^")
        If idx = -1 Then idx = 0 Else idx += "Octer-stream^Base64^".Length
        Dim bytes = Convert.FromBase64String(b64.Substring(idx))
        pts.Clear()
        count = 0 : m = 0
        For Each b In bytes
            If b > m Then m = b
            pts.Add(New Point(count, b))
            count += 1
        Next
        Me.Invalidate()
    End Sub
    Protected Overrides Sub OnPaint(pe As PaintEventArgs)
        MyBase.OnPaint(pe)
        If pts.Count = 0 Then Return
        Dim dx = (Me.Width - 20) / count, dy = (20 - Me.Height) / m
        With pe.Graphics
            .ScaleTransform(dx, dy)
            .TranslateTransform(10 / dx, (-50 - Me.Height))
            .DrawCurve(Pens.Black, pts.ToArray)
        End With
    End Sub
End Class

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    Private Sub Button1_Click(sender As Object, e As EventArgs) Handles Button1.Click
        Dim s = "OBX|32|ED|15000^WBC Histogram. Binary^99MRC||^Application^Octer-stream^Base64^AAAAAAAAAAAAAAAAAAAAAAAAAAAAAQEBAgIDAwUGCg4TGiIuOklYaX2OoLHD1OLu+P3//vny593Sw7Snmo1/dWthWFBJQjw2Mi8sKSclIyIgHx4cHBoaGBcWFBQTExISERAQEA8PDw4MDAsKCgoJCAgIBwcGBwcGBgYGBQQEBAQDBAMDAwMDAgICAgICAgEBAQEBAQEBAQEBAQEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA=="
        ObxGraph1.Draw(s)
    End Sub

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Imports Excel = Microsoft.Office.Interop.Excel

Public Class Form1
    Private Sub Button1_Click(sender As Object, e As EventArgs) Handles Button1.Click
        Dim s = "OBX|32|ED|15000^WBC Histogram. Binary^99MRC||^Application^Octer-stream^Base64^AAAAAAAAAAAAAAAAAAAAAAAAAAAAAQEBAgIDAwUGCg4TGiIuOklYaX2OoLHD1OLu+P3//vny593Sw7Snmo1/dWthWFBJQjw2Mi8sKSclIyIgHx4cHBoaGBcWFBQTExISERAQEA8PDw4MDAsKCgoJCAgIBwcGBwcGBgYGBQQEBAQDBAMDAwMDAgICAgICAgEBAQEBAQEBAQEBAQEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA=="
        GraphToExcel(s)
    End Sub

    Private Sub GraphToExcel(b64 As String)
        Dim idx = b64.IndexOf("Octer-stream^Base64^")
        If idx = -1 Then idx = 0 Else idx += "Octer-stream^Base64^".Length
        Dim bytes = Convert.FromBase64String(b64.Substring(idx))
        Dim app = New Excel.Application
        app.Visible = True
        Dim wb = app.Workbooks.Add
        Dim sheet As Excel.Worksheet = wb.Sheets(1)
        For i = 1 To bytes.Count
            sheet.Range("A" & i).Value2 = bytes(i - 1)
        Next
        Dim charts As Excel.ChartObjects = sheet.ChartObjects()
        Dim chartObject = charts.Add(60, 10, 600, 300)
        Dim chart = chartObject.Chart
        Dim rng = sheet.Range("A1:A" & bytes.Count.ToString)
        chart.SetSourceData(rng)

        chart.ChartType = Excel.XlChartType.xlLine
        chart.ChartWizard(Source:=rng)
    End Sub
End Class

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Imports System.ComponentModel

Public Class LIS_Graph
    Inherits PictureBox

    Public Class MsgInfo
        Public Property MessageType As String
        Public Property SequenceId As String
        Public Property DataType As String
        Public Property ObservationID As String
        Public Property ObservationName As String
        Public Property EncodeSys As String
        Public Property Value As String
        Public Property Units As String
        Public Property RefRange As String
        Public Sub Clear()
            MessageType = "" : SequenceId = "" : DataType = "" : ObservationID = "" : ObservationName = "" : EncodeSys = "" : Value = "" : Units = "" : RefRange = ""
        End Sub
        Public Overrides Function ToString() As String
            Dim sb As New Text.StringBuilder
            For Each p In [GetType].GetProperties(Reflection.BindingFlags.Public Or Reflection.BindingFlags.Instance)
                Dim s As String = p.GetValue(Me)
                sb.AppendLine(String.Format("{0}: {1}", p.Name, s))
            Next
            Return sb.ToString
        End Function

    End Class

    Private _graphBytes As Byte()
    Private _lblInfo As New Label With {.AutoSize = False, .Width = 240, .Height = 140, .BorderStyle = BorderStyle.FixedSingle, .Padding = New Padding(5)}
    Public Sub New()
        Info = New MsgInfo
        SetStyle(ControlStyles.OptimizedDoubleBuffer, True)
        Controls.Add(_lblInfo)
    End Sub
    Public Sub New(msg As String)
        Info = New MsgInfo
        SetStyle(ControlStyles.OptimizedDoubleBuffer, True)
        Message = msg
    End Sub

    <TypeConverter(GetType(PointFConverter)), DefaultValue(GetType(PointF), "1.4, 1.0")> Public Property UnitsScale As PointF = New PointF(1.4F, 1.0F)
    <DefaultValue(GetType(Point), "50, 50")> Public Property LinesStep As Point = New Point(50, 50)
    <DefaultValue(GetType(Point), "20, 20")> Public Property Offset As Point = New Point(20, 20)
    <DefaultValue(True)> Public Property CursorLines As Boolean = True
    <DefaultValue(True)> Public Property ShowInfo As Boolean = True
    <Browsable(False)> Public ReadOnly Property Info As MsgInfo
    Public WriteOnly Property Message As String
        Set(value As String)
            Parse(value)
        End Set
    End Property

    Public Sub RefreshGraph()
        Image = CreateGraph()
        _lblInfo.Visible = ShowInfo
    End Sub

    Private ReadOnly Property GraphSize As Size
        Get
            Return New Size(Width - Offset.X * 2, Height - Offset.Y * 2)
        End Get
    End Property
    Private ReadOnly Property GraphScale As PointF
        Get
            If _graphBytes Is Nothing OrElse _graphBytes.Length = 0 Then Return New PointF(1.0, 1.0)
            Dim sz = GraphSize
            Return New PointF(sz.Width / _graphBytes.Count, sz.Height / _graphBytes.Max)
        End Get
    End Property

    Private Sub Parse(lisString As String)
        Clear()
        Dim parts = lisString.Split("|"c)
        Info.MessageType = parts(0)
        If parts.Length > 1 Then Info.SequenceId = parts(1)
        If parts.Length > 2 Then Info.DataType = parts(2)
        If parts.Length > 3 Then
            Dim observation = parts(3)
            If observation <> "" Then
                Dim oParts = observation.Split("^"c)
                Info.ObservationID = oParts(0)
                Info.ObservationName = oParts(1).Replace(". ", ".")
                Info.EncodeSys = oParts(2)
            End If
        End If
        If parts.Length > 5 Then Info.Value = parts(5)
        If Info.Value.StartsWith("^Application^Octer-stream^Base64^") Then
            _graphBytes = Convert.FromBase64String(Info.Value.Replace("^Application^Octer-stream^Base64^", ""))
            Info.Value = "Base64 encoded graph data"
            Image = CreateGraph()
        End If
        If parts.Length > 6 Then Info.Units = parts(6)
        If parts.Length > 7 Then Info.RefRange = parts(7)
        _lblInfo.Visible = ShowInfo
        _lblInfo.Text = Info.ToString
    End Sub

    Private Sub Clear()
        _graphBytes = Nothing
        Info.Clear()
        Image = Nothing
    End Sub

    Private Function CreateGraph() As Bitmap
        If _graphBytes Is Nothing OrElse _graphBytes.Length = 0 Then
            Return Nothing
        End If

        Dim graph As New Bitmap(ClientSize.Width, ClientSize.Height)
        Dim pts As New List(Of Point)
        Dim count = 0, sz = GraphSize, scale = GraphScale
        For Each b In _graphBytes
            pts.Add(New Point(count * scale.X + Offset.X, b * scale.Y + Offset.Y))
            count += 1
        Next
        Dim w = sz.Width + Offset.X, h = sz.Height + Offset.Y
        Using g = Graphics.FromImage(graph)
            g.CompositingQuality = Drawing2D.CompositingQuality.HighQuality
            g.TextRenderingHint = Drawing.Text.TextRenderingHint.AntiAliasGridFit
            Using f As New Font("Arial", 8, FontStyle.Regular, GraphicsUnit.Point)
                Using linePen = New Pen(Color.Black) With {.DashStyle = Drawing2D.DashStyle.Dash}
                    Dim sf As New StringFormat With {.Alignment = StringAlignment.Far, .LineAlignment = StringAlignment.Center}
                    For i = 0 To _graphBytes.Max * UnitsScale.Y Step LinesStep.Y
                        Dim y = h - i * scale.Y / UnitsScale.Y
                        Dim p = If(i = 0, Pens.Black, linePen)
                        g.DrawLine(p, Offset.X, y, w, y)
                        g.DrawString(i, f, Brushes.Black, Offset.X, y, sf)
                    Next
                    sf = New StringFormat With {.Alignment = StringAlignment.Center, .LineAlignment = StringAlignment.Near}
                    For i = 0 To count * UnitsScale.X Step LinesStep.X
                        Dim x = Offset.X + i * scale.X / UnitsScale.X
                        Dim p = If(i = 0, Pens.Black, linePen)
                        g.DrawLine(p, x, 0, x, h)
                        g.DrawString(i, f, Brushes.Black, x, h, sf)
                    Next
                End Using
            End Using
            g.ScaleTransform(1.0F, -1.0F)
            g.TranslateTransform(0.0F, -h - Offset.Y)
            g.DrawCurve(Pens.Black, pts.ToArray)
            g.ResetTransform()

            'If ShowInfo Then
            '    Dim rc = New Rectangle(w - 240, Offset.Y, 240, 130)
            '    g.FillRectangle(Brushes.White, rc)
            '    g.DrawRectangle(Pens.Black, rc)
            '    rc.Inflate(-5, -5)
            '    g.DrawString(Info.ToString, Font, Brushes.Black, rc)
            'End If
        End Using
        Return graph
    End Function

    Private Sub LIS_Graph_MouseMove(sender As Object, e As MouseEventArgs) Handles Me.MouseMove
        If Not CursorLines OrElse _graphBytes Is Nothing OrElse _graphBytes.Length = 0 Then Return
        Refresh()
        Dim scale = GraphScale, sz = GraphSize
        Dim w = sz.Width + Offset.X, h = sz.Height + Offset.Y
        If e.X < Offset.X OrElse e.X > w OrElse e.Y < Offset.Y OrElse e.Y > h Then Return
        Using p = New Pen(Brushes.Red) With {.DashStyle = Drawing2D.DashStyle.Dash}
            Using g = Graphics.FromHwnd(Handle)
                g.DrawLine(p, 0, e.Y, Width, e.Y)
                g.DrawLine(p, e.X, 0, e.X, Height)
                Dim sf As New StringFormat With {.LineAlignment = StringAlignment.Far}
                Dim dX = If(e.X > GraphSize.Width / 2 + Offset.X, -80, 3)
                Dim pt = New Point(e.X + dX, e.Y - 3)
                Dim x As Integer = (e.X - Offset.X) * UnitsScale.X / scale.X,
                    y As Integer = (h - e.Y) * UnitsScale.Y / scale.Y
                g.DrawString(String.Format("x = {0}; y = {1}", x, y), Font, Brushes.Red, pt, sf)
            End Using
        End Using
    End Sub
    Private Sub LIS_Graph_MouseLeave(sender As Object, e As EventArgs) Handles Me.MouseLeave
        Refresh()
    End Sub
    Private Sub LIS_Graph_SizeChanged(sender As Object, e As EventArgs) Handles Me.SizeChanged
        Image = CreateGraph()
        _lblInfo.Location = New Point(GraphSize.Width + Offset.X - _lblInfo.Width, Offset.Y)
    End Sub

End Class

Public Class PointFConverter
    Inherits ExpandableObjectConverter

    Public Overrides Function CanConvertFrom(context As ITypeDescriptorContext, sourceType As Type) As Boolean
        If sourceType = GetType(String) Then
            Return True
        Else
            Return MyBase.CanConvertFrom(context, sourceType)
        End If
    End Function

    Public Overrides Function ConvertFrom(context As ITypeDescriptorContext, culture As System.Globalization.CultureInfo, value As Object) As Object
        If TypeOf value Is String Then
            Try
                Dim s As String = DirectCast(value, String)
                Dim converterParts As String() = s.Split(";"c)
                Dim x As Single = 0.0F, y As Single = 0.0F
                If converterParts.Length > 1 Then
                    x = Single.Parse(converterParts(0).Trim())
                    y = Single.Parse(converterParts(1).Trim())
                ElseIf converterParts.Length = 1 Then
                    x = Single.Parse(converterParts(0).Trim())
                End If
                Return New PointF(x, y)
            Catch
                Throw New ArgumentException("Cannot convert [" + value.ToString() + "] to pointF")
            End Try
        End If
        Return MyBase.ConvertFrom(context, culture, value)
    End Function

    Public Overrides Function ConvertTo(context As ITypeDescriptorContext, culture As System.Globalization.CultureInfo, value As Object, destinationType As Type) As Object
        If destinationType = GetType(String) AndAlso TypeOf value Is PointF Then
            Dim pt As PointF = value
            Return String.Format("{0}; {1}", pt.X, pt.Y)
        End If

        Return MyBase.ConvertTo(context, culture, value, destinationType)
    End Function
End Class

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   Private Sub Form1_Load(sender As Object, e As EventArgs) Handles MyBase.Load
        Dim graph = New LIS_Graph With {.Dock = DockStyle.Fill}
        Controls.Add(graph)
        graph.Message = "OBX|32|ED|15000^WBC Histogram. Binary^99MRC||^Application^Octer-stream^Base64^AAAAAAAAAAAAAAABAgQHDRcmO1Z3nMPg9P/98+HKsZl8aFdGMyUfHBwcHR8iJy02QUpLTU5PT09PTUxKSEZEQkBAPz4+PT09Pj49PDo5ODg3Nzg6PD5AQ0ZISUpMTU9RU1VWWFlZWlpaWlpaWlpbW1tbW1tcXV5fYGBhYWBgXl1bWVdVU1JQT01MSkhGREJAPj07OTg2NDMxLy0sKignJSQi"
    End Sub

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