Connection issues using Skype for Business and Outlook 2016 on a Windows 7 machine.

Has anyone seen an issue where trying to run Skype for Business 2016 and Outlook 2016 on a Windows 7 machine causes Outlook to not be able to connect.

Skype is running,
When I try to open Outlook 2016, I get an error saying 'We are unable to connect right now. Please check your network and try again later."

Error Message
Steven ReidHead of ITAsked:
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David Johnson, CD, MVPOwnerCommented:
Can't reproduce it.. they use different ports and ip addresses
Is this an issue that started on an established implementation or is it happening as part of a new one? Are your certificates properly assigned not expired, valid, and trusted on the affected client, and does your edge network reverse proxy work properly? Have you tried looking at Outlook connection diagnostics on the Windows Tray?  Just a few things I would start with.
Steven ReidHead of ITAuthor Commented:
this is a current machine that has recently had Skype installed, but was working before that.

it is strange, but the machine is saying no internet connection, but does have connectivity.
even if you go to the backstage for Excel, it now says no internet connection.
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So if this is a single client, maybe you should see if there is a firewall policy preventing Internet access- or maybe a common port is being blocked. One port that comes to mind is 5060- sounds like a problem specific to that client or IP address. Also make sure that you network settings are correct!
Steven ReidHead of ITAuthor Commented:
it turned out to be a temporary issue.   it resolved itself by the end of the day.

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Steven ReidHead of ITAuthor Commented:
Thanks for all your suggestions.!
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