Loop Guard and Root Guard on Cisco Switches

Root guard on the port makes it the only port that can send and receive data to it's opposing switch. This means that port is designated as root for the entire switch no matter how many uplinks to another switch you have. If you don't have any Root ports, then you would institute loop guard on switch ports to an opposing switch that you don't want to come up.

These only function if you have multiple uplinks to opposing switches, otherwise they are not needed with only a single uplink.

in this case , do we have to go to each Non Designated Ports in the Network and configure Loop Guard and to each Designated Port and configure Root Guard ?

For those features, yes.

I am assuming in the Network that has no Layer 2 redundant links this is not needed at all, except on the Access ports where we need to configure Port Fast and BPDU Guards.

Actually, things like Root Guard, Port Fast, BPDU Guard, etc., are not required.  They are enhancements.  They improve the behavior of STP.

As for Root Guard, its purpose is to enforce the designed topology.  Basically, it allows the network administrator to prevent rogue or misconfigured switches from becoming the root and changing the network topology.  

For example, you have made one of your switches the root because that creates the best topology for your network.  If someone connects a new switch to one of your access switches and this new switch has a lower bridge ID, then it will become the root. There will then be a brief outage as the network converges to the new topology built around the new root.  With Root Guard configured, when that new switch sent out its BPDU with the lower Bridge ID, it would be ignored.

In real world do they have to  use those enhancements  or they go for a design that does not need those enhancements, for instance the one show on this diagram:
https://www.experts-exchange.com/questions/28965543/L2-L3-Switch-configuration.html

the only place where I see , on the diagram shown on the above line, that Portfast and Bpduguard are a must to be configured  on Access switch ports connecting to computers.

No, the enhancements are not required.  They just improve the performance of spanning-tree.

But I ALWAYS use them whenever possible.

so the design as shown on this link, is the only solution to prevent STP Loops and TCN ?

Thank you Guys!