how does the ingestion of micro-plastics interfere with estrogen?

GMartin
GMartin used Ask the Experts™
on
Hello and Good Afternoon Everyone,

            As an extension from a previously closed post, I recently read a theory which is being thrown around to help explain why Japanese women raised in Japan have very little breast cancer, while (genetically) Japanese women raised in the US have about the same rate as European-American women.   The theory suggest that plastics leach a material that mimics estrogen.   As clearly indicated within a previously closed post, the ingestion of micro-plastics over an extended period of time can certainly lead to a variety of physical abnormalities.  That said, I am wondering how micro-plastics can mimic estrogen.  Does this happen at a molecular level, meaning, the micro-plastics take on a similar structure as estrogen?  Or, does it try to mimic estrogen at a functional level?

            Any feedback given here will be greatly appreciated.

            Thank you

             George
Comment
Watch Question

Do more with

Expert Office
EXPERT OFFICE® is a registered trademark of EXPERTS EXCHANGE®
Most Valuable Expert 2013
Commented:
Most polymers demonstrate some form of estrogenic activity either in that they mimic estrogens or  that they antagonize (reduce the effect) of naturally occuring estrogens.  Much of the work is theoretical and there are debates over whether this activity is significant and if there are causal relationships with health effects.

A science-based primer here:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222987/

Author

Commented:
Thank you very much for answering my question.  As always, it is greatly appreciated :-)

George

Do more with

Expert Office
Submit tech questions to Ask the Experts™ at any time to receive solutions, advice, and new ideas from leading industry professionals.

Start 7-Day Free Trial