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Fix problem: Office 365 apps on Windows 10 Pro PC not opening or able to be repaired after update for Microsoft Office


On one of our Windows 10 Pro PCs, we have Office 365 setup and installed.

This is mostly used for emails through Outlook and using apps such as Microsoft Word and Excel.

For a while there was a prompt to update Microsoft Office so we updated it yesterday.

After restarting the PC, we have found that Microsoft Office has stopped working properly.

1. Restarting the PC again did not change anything.

2. After clicking on Microsoft Outlook or other apps such as Word and Excel, an error message pops up: "Something went wrong- We couldn't start your program. Please try starting it again. Error Code: 0x426-0x0".

3. I went to services on PC through running "services.msc", clicked on "Microsoft Office Click-to-Run Service", Properties, then tried starting this service. This error message pops up: "Windows could not start the Microsoft Office Click-to-Run Service service on Local Computer. Error 193: 0xc1"

4. Found file "OfficeClickToRun.exe" and tried to run. Following error message pops up: "This app can't run on your PC. To find a version for your PC, check with the software publisher".

5. Tried to "Repair" Microsoft Office 365 - Business program in "Programs and Features" by clicking on "Change". The following error message appeared: "An error occurred while trying to uninstall Microsoft Office 365 Business -en-us. It may have already been uninstalled. Would you like to remove Microsoft Office 365 Business - en-us from the Programs and Features list?"

We clicked on "No".

Any ideas what could of caused this problem?

What do you think is the best thing to do to get this working again?

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Jackie Man
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For a while there was a prompt to update Microsoft Office so we updated it yesterday.

Uninstall the update is your only option.
Hi there! :)

As mentioned by @Jackie Man, you may need to uninstall the update. In other words, you will have to revert Office back to an earlier version which worked for you. You may refer to the article below which is provided by the official Microsoft Support  Team.


By default, Click-to-Run installations of Microsoft Office 2016 are configured to automatically update your Office installation when new updates are made publicly available. Occasionally, you may have to revert to an earlier version of an Office 2016 Click-to-Run installation. For example, an automatic update may introduce unexpected behavior by one of your Office applications. In this case, you may want to revert to the previous version until a new version is released that addresses the issue you experienced.
If rollback to previous version doesn't work then uninstall and create a new installation config file @ Install using setup.exe \config.xml, the user settings should be maintained
you can also use system restore
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