Hyper-V replication between data centers

So, I have two data centers.  One is in Houston and one is in Colorado.

In each data center, I have one Hyper-V stack.  Several hosts, many VMs in each data center.

I'd like to send replicas from data center 1 to data center 2 over our internet connection.

Now I do this internally, between sites, etc, but this is my first foray into doing it between data centers over the net.

So, should I do it this way or not?  Obvousily I'd use certs.

Is there a better way?

Is it just a matter of directing 443 to my hosts and making my connections?

Lots of questions and I'd like lots of feedback.

I know it'll be tough to assign points and points hardly seem worth replying to such an overbroad question, but hey, I LOVE EE so here I am.

Speak oh wise ones!