We help IT Professionals succeed at work.
Get Started

What is the difference between direct injection and other types of LCMS

48 Views
Last Modified: 2020-02-11
Can any one help with LC/MS R packages?

The xcms R package for LCMS is very versitile.  It distinguishes between Grouping FTICR-MS data with xcms, LCMS and LCMSMS.  

Quoting from the documentation
This document describes how to use xcms for the analysis of direct injection mass spec data, including peak detection, calibration and correspondence (grouping of peaks across samples). Prior to any other analysis step, peaks have to be identified in the mass spec data. In contrast to the typical metabolomics workflow, in which peaks are identified in the chromatographic (time) dimension, in direct injection mass spec data sets peaks are identified in the m/z dimension. xcms uses functionality from the MassSpecWavelet package to identify such peaks.
 

I cannot find any information related to direct injection.  I understand FTCIR-MS and the reason why peaks can be identified in the m/z dimension, but I don't understand the concept of direct injection and whether this concept is associated with FTICR-MS only and not with LC/MS or LC.MS/MS.
Comment
Watch Question
This question hasn't been answered yet.
While you wait, find out how you can maximize your capability with the most trusted tool in IT.
Explore More Ask a Question
Why Experts Exchange?

Experts Exchange always has the answer, or at the least points me in the correct direction! It is like having another employee that is extremely experienced.

Jim Murphy
Programmer at Smart IT Solutions

When asked, what has been your best career decision?

Deciding to stick with EE.

Mohamed Asif
Technical Department Head

Being involved with EE helped me to grow personally and professionally.

Carl Webster
CTP, Sr Infrastructure Consultant

An Experts Exchange subscription includes unlimited access to online courses.

Get Started
Ask ANY Question

Connect with Certified Experts to gain insight and support on specific technology challenges including:

  • Troubleshooting
  • Research
  • Professional Opinions
Did You Know?

We've partnered with two important charities to provide clean water and computer science education to those who need it most. READ MORE