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Upgrading ESXI 4.1

Last Modified: 2020-02-12
I have a server running ESXi 4.1 at my house.  I have a virtual computer that I want to upgrade to Windows 10 and it is not working since apparently ESXi 4.1 does not support Windows 10.  (I even tried a fresh install and it would not run the installer.)
So it looks like i need to upgrade my Hypervisor.  The server has 128GB of memory and it has 4 physical CPU's each with 4 cores.  I believe that Hypervisor 6.7 only supports 2 physical CPU's.  Since I do not run too many virtual machines I do not think this is an issue as long as it will just ignore 2 of the CPU's.  So the first question is will it just ignore 2 of the CPU's?  (or will it just not work?)
It is currently running ESXi 4.1 from a USB drive.  Can I just replace the USB drive with ESXi 6.7, boot, and have everything recognized?  Is there anything special I need to do to make it recognize the existing Datastore so I can bring up the existing virtual machines?
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