Using Cisco CCUM 11.5 and can't connect to my ITSP

A little clarification needed...
If your phones are on the Internet and connecting to an 11.5 Call Manager, they'll need to have an Expressway server to proxy the connection. If the phones are on your network, all they need is a valid DHCP Option 150 with the IP of your Call Manager and IP connectivity to your Call Manager.
Which method are you using in this case?

they have Dhcp option 150 from Server 2016 and has the firmware and configs from tftp32 server. In other words server 2016 has the ip address of the tftp server?

Typically the Call Manager is used as the TFTP server natively. Using TFTP32 adds necessary complexity if the phones have IP Connectivity to the Call Manager.

ok i'll try that

Thanks for the advise! I was able to use the call-manager as a tftp server with option 150. I'm just still trying to figure out how to create a sip connection with my ITSP so that I can dial out to the world.

I was able to call myself with my DX650, 8961 and 8941 phones.

Typically, SIP connections from Call Manager go through a CUBE (Cisco Unified Border Element ) first. CUBE runs on ISRs, usually 4300 series routers if you're going with new stuff. It is "possible" to make a SIP connection to a TSP with Call Manager alone but it is not recommended and usually not supported by the TSP.

Good, because my ISR 2921 has CUBE? and also an ISR board with memory for Unity, When I purchased the router it had CME 12.0 on it but I wanted to use CUCM.