Autoreload Database linked from Sharepoint

You mean, the database is stored in SharePoint? Or you use a list in SharePoint?
From the vb site, objects may have a .refresh method.
But your description is too generic to give a more detailed answer.

You can use the Button.Click event to trigger something. But it depends, how your form is connected to the database.  

I'm using a list in sharepoint as database.
Its linked to local access program and shared with other people