Dell 5080 won't boot

On a dell unit, I have a user that all of sudden started receiving this message of no boot devices.  I'm reading that it might have to do with secure boot needing to be turned off and then it fixes the problem, but no matter what I do, I can't get into bios to look at it.  Every time I turn the computer on, it immediately goes to this screen.  Any ideas what I can do to solve this issue.