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Powerpoint files suddenly tripping out Microsoft Upload Center/Access denied messages

Suddenly in the past few days one of our users has lost the ability to open PPT files. He's prompted with a Microsoft Upload Center message, which is on occasion in addition to a message saying "Access denied. Contact your system administrator." His is in an AD group that has, and always had, modify rights to those files.

This is for Office 2016 Standard on Windows 10 Pro.
--Renamed the %userprofile%\AppData\Local\Microsoft\Office\16.0\OfficeFileCache folder and recreated it. Deleted the old one.
--Reinstalled Office 2016.
--Gave user explicit rights to entire folder structure containing the PPTs in question.

We're at a loss...can anyone assist? Thanks.

Jazz Marie Kaur

Hi Kevin M,

I added the Microsoft PowerPoint as a topic tag to your post since its relevant and will help alert more Experts to this issue well-versed in it.

Reinstalled Office 2016.

Use Microsoft's scrubber uninstaller tool, you may see different results its helped me in the past and others in EE, see option 2:
- https://support.microsoft.com/en-us/office/uninstall-office-from-a-pc-9dd49b83-264a-477a-8fcc-2fdf5dbf61d8
Make sure there are no pending W10 updates nor ones from Microsoft Office under the File menu.
Check Event Viewer logs for error codes under Application, etc. sections comb through a little
Possibly install Process Explorer or ProcMonfor error tracing further and capturing anything else causing interference, can help showcase backend events or source of the access denial
- https://docs.microsoft.com/en-us/sysinternals/downloads/procmon
- https://docs.microsoft.com/en-us/sysinternals/downloads/process-explorer
Are Word and Excel files completely fine? Did you verify other Office files are okay?
Where are the PPT files stored...are these shared files and what happens opening from the desktop vs File Explorer or changing the file location or copying it out elsewhere? Did they create these PowerPoint files or happens with ones they create and share? Can you test one on the desktop - opening is it fine or just from the share its an issue?
Can they open, download PPT files from e.g. the web and open them or those error too?
A thought I had was clearing Credential Manager out of W10 for Office entries then signing back into Office apps.
A thought was running SFC or even the DISM repair command lines, but I do not think that will resolve this, be cautious and have a system restore point if you try either but it could be an issue with W10 rather Office possibly
I would test creating a new user profile on the OS and comparing as a last resort and migrate their data over there if the profile is damaged

ASKER CERTIFIED SOLUTION

Kevin M

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Jazz Marie Kaur

You're welcome! Glad its resolved! Profile hiccups are never fun. Thanks for sharing your solution!