#!c:/Python27/python.exe -u
import PythonMagick
img = PythonMagick.Image('Hello.pdf')    # use your full path here
img.write('original.jpeg')

imgLowRes = PythonMagick.Image(img)  # make a copy
imgLowRes.sample('220x')
imgLowRes.write('lowRes.jpeg')

img.sample('48x')
img.write('thumb.jpeg')